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. Author manuscript; available in PMC: 2009 Apr 23.
Published in final edited form as: Endocrinology. 2001 May;142(5):1737–1743. doi: 10.1210/endo.142.5.8155

Fig. 4.

Fig. 4

A, Comparison of potencies among GnRH analogs that differ at a single residue, position 8. ED50 is plotted for four different GnRH agonists for IP production in COS-1 cells transiently transfected with the H. burtoni GnRH-R or the goldfish GnRH-R subtypes (6). B, Comparison of presumed binding regions of three GnRH-Rs by amino acids and by polarities of amino acids. The first extracellular loop (EC1) and the third extracellular loop (EC3) are compared for H. burtoni and the two goldfish GnRH-R forms.