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IC50 values for the competitive binding of 125I-[His5,D-Tyr6]GnRH with GnRH agonists in COS-1 cells transiently transfected with the H. burtoni GnRH-R
| Peptide | IC50 (nM) |
|---|---|
| [His5,Trp7,Tyr8]GnRH (GnRH2) | 14.2 ± 5.5 |
| [Trp7,Leu8]GnRH (GnRH3) | 2486.7 ± 888.7 |
| [Arg8]GnRH (mGnRH1) | 2615 ± 2821.4 |
| [Ser8]GnRH (sbGnRH1) | 30233.3 ± 8575.7 |
Data are calculated as the mean of three separate experiments.
