Table 2.
Case | Method |
|||||||
---|---|---|---|---|---|---|---|---|
FDR | pFDR | SAM | MD-MM | |||||
Errors | Power | Errors | Power | Errors | Power | Errors | Power | |
1 | 10 | 0 | 10 | 0 | 9.6 | 3.6 | 9.0 | 9.8 |
2 | 8.1 | 19.6 | 8.1 | 20 | 7.5 | 25.5 | 6.5 | 35.4 |
3 | 6.8 | 33.2 | 6.7 | 34.4 | 3.9 | 61 | 3.8 | 63.9 |
4 | 10 | 0 | 10 | 0 | 10 | 0 | 5.8 | 43.8 |
| ||||||||
5 | 50 | 0 | 49.9 | 0.1 | 48.2 | 3.7 | 40.1 | 17.1 |
6 | 35.2 | 30.5 | 33.8 | 33.8 | 32.2 | 36.5 | 26.2 | 49.4 |
7 | 24.4 | 52.6 | 21.9 | 58.9 | 23.1 | 55.1 | 14.6 | 72.8 |
8 | 50 | 0 | 50 | 0 | 50 | 0 | 24.7 | 51.8 |
| ||||||||
9 | 50 | 0 | 50 | 0 | 49.9 | 0.1 | 22.1 | 56.9 |
10 | 49 | 2 | 48.9 | 2.2 | 48.8 | 2.5 | 18.6 | 64.1 |
11 | 45.9 | 8.3 | 45.3 | 9.7 | 42.5 | 15.4 | 12.2 | 77.8 |
12 | 50 | 0 | 50 | 0 | 50 | 0.1 | 15.0 | 71.8 |
| ||||||||
13 | 50 | 0 | 49.8 | 0.4 | 42.4 | 15.6 | 35.8 | 31.3 |
14 | 29 | 43.2 | 27.3 | 47.3 | 25.7 | 50.6 | 21.9 | 58.5 |
15 | 24.2 | 52.8 | 21.8 | 58.9 | 19.7 | 63.2 | 14.8 | 72.4 |
16 | 50 | 0 | 50 | 0 | 50 | 0 | 22.6 | 56.3 |
| ||||||||
Ave | 33.9 | 15.6 | 33.3 | 17.4 | 32.1 | 20.4 | 18.2 | 52.5 |
Power=100[1−(# false negatives/# true DE)]
Errors=100(# false positives + # false negatives)/N.
For MD-MM, the null distribution was always defined as the distribution centered at 0 with smallest variance, genes in all other distributions were declared DE.