Skip to main content
. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: Comput Stat Data Anal. 2009 Mar 15;53(5):1566–1576. doi: 10.1016/j.csda.2008.06.011

Table 2.

Total error rate (%) and power (%) for alternative methods of microarray analysis for cases given in Table 1.

Case Method
FDR pFDR SAM MD-MM

Errors Power Errors Power Errors Power Errors Power
1 10 0 10 0 9.6 3.6 9.0 9.8
2 8.1 19.6 8.1 20 7.5 25.5 6.5 35.4
3 6.8 33.2 6.7 34.4 3.9 61 3.8 63.9
4 10 0 10 0 10 0 5.8 43.8

5 50 0 49.9 0.1 48.2 3.7 40.1 17.1
6 35.2 30.5 33.8 33.8 32.2 36.5 26.2 49.4
7 24.4 52.6 21.9 58.9 23.1 55.1 14.6 72.8
8 50 0 50 0 50 0 24.7 51.8

9 50 0 50 0 49.9 0.1 22.1 56.9
10 49 2 48.9 2.2 48.8 2.5 18.6 64.1
11 45.9 8.3 45.3 9.7 42.5 15.4 12.2 77.8
12 50 0 50 0 50 0.1 15.0 71.8

13 50 0 49.8 0.4 42.4 15.6 35.8 31.3
14 29 43.2 27.3 47.3 25.7 50.6 21.9 58.5
15 24.2 52.8 21.8 58.9 19.7 63.2 14.8 72.4
16 50 0 50 0 50 0 22.6 56.3

Ave 33.9 15.6 33.3 17.4 32.1 20.4 18.2 52.5
*

Power=100[1−(# false negatives/# true DE)]

Errors=100(# false positives + # false negatives)/N.

For MD-MM, the null distribution was always defined as the distribution centered at 0 with smallest variance, genes in all other distributions were declared DE.