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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Mod Pathol. 2008 May;21(Suppl 2):S37–S43. doi: 10.1038/modpathol.2008.10

Table 1.

Average prevalence of mutations in thyroid cancer

Tumor Type Prevalence
Papillary Carcinoma
 BRAF 45%
 RET/PTC 20%
 RAS 10%
 TRK <5%
Follicular Carcinoma
 RAS 45%
 PAX8-PPARy 35%
 PIK3CA <10%
 PTEN <10%
Medulllary Carcinoma Carcinoma
 familial forms RET >95%
 sporadic RET 50%
Poorly Differentiated Carcinoma
 RAS 35%
 β-catenin (CTNNB1) 20%
 TP53 20%
 BRAF 15%
Anaplastic Carcinoma
 TP53 70%
 β-catenin (CTNNB1) 65%
 RAS 55%
 BRAF 20%