Fig: 2.
Percent suppression of the proliferation of baboon CD4+CD25neg cells. Naïve CD4+CD25high Treg cells, ex-vivo expanded CD4+ T (5×104) expanded without and with rapamycin and purified CD4+CD25high obtained from ex-vivo expanded CD4+ T in presence of Rapamycin were co-cultured with autologus CD4+CD25neg effector (Teff) cells (5×104) and stimulated with irradiated pig PBMCs. Percent suppression of CD4+CD25neg cell proliferation was assessed by using the above mentioned formula (p value *p<0.02, **P<0.03).