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. Author manuscript; available in PMC: 2010 Apr 21.
Published in final edited form as: Neuroscience. 2009 Feb 25;160(1):42–50. doi: 10.1016/j.neuroscience.2009.02.031

Fig. 2. Depolarization-induced formation of synaptic spinules at excitatory synapses in hippocampal slice cultures.

Fig. 2

Synaptic spinules were not found in samples fixed immediately without treatment (A), or in experimental controls (C, 2 min in normal medium). After high K+ depolarization, spinules (arrows in B, D) were found in some synaptic terminal profiles. The postsynaptic densities (PSD, double arrowheads) were relatively thin in A and C compared to those in B and D. Scale bar = 0.1 μm.