TABLE 1.
Acronym | Acronym translationa | Biological processa | Functiona |
---|---|---|---|
ABP1 | Actin Binding Protein | Actin cortical patch assembly; establishment of cell polarity | Actin-binding protein; activation of the Arp2/3 complex |
CDC55 | Cell Division Cycle | Protein amino acid dephosphorylation; actin filament organization; translation; cell bud growth; pseudohyphal growth; mitotic cell cycle spindle assembly checkpoint; negative regulation of exit from mitosis | B regulatory subunit of protein phosphatase 2A and ceramide-activated protein phosphatase; protein serine/threonine phosphatase activity |
EXO70 | EXOcyst | Bipolar bud site selection; cytokinesis; exocytosis; Golgi to plasma membrane transport vesicle docking during exocytosis; vesicle fusion | Phosphatidylinositol 4,5-bisphosphate binding; protein binding |
PEP4 | carboxyPEPtidase Y-deficient | Cellular response to starvation; microautophagy; formation of a cellular spore during sporulation; vacuolar protein catabolic process | Vacuolar aspartyl protease (proteinase A) |
PPH21 and PPH22 | Protein PHosphatase | Actin filament organization; cell bud growth; G1/S transition of mitotic cell cycle; mitotic cell cycle spindle assembly checkpoint; protein amino acid dephosphorylation; translation | Catalytic subunit C of protein phosphatase 2A; protein serine/threonine phosphatase activity; functionally redundant |
RTS1 | Rox Three Suppressor | Meiotic chromosome cohesion translation protein amino acid dephosphorylation | B regulatory subunit of PP2A |
RVS161 | Reduced Viability upon nutrient Starvation | Endocytosis; polar budding; response to osmotic stress; mating | Cytoskeletal protein binding |
RVS167 | Reduced Viability upon nutrient Starvation | Endocytosis; polar budding; response to osmotic stress | Cytoskeletal protein binding |
SAC6 | Suppressor of ACtin mutations | Actin filament organization endocytosis; polar budding; response to osmotic stress | Actin filament binding; protein binding, bridging |
SEC8 | SECretory | Bipolar bud site selection; cytokinesis; exocytosis; Golgi to plasma membrane transport vesicle docking during exocytosis; vesicle fusion | Protein binding |
SEC20 | SECretory | SNAP receptor activity | Vesicle fusion; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
SIT4 | Sporulation-Induced Transcript | G1/S transition of the mitotic cycle; actin cytoskeleton and cell wall organization; dephosphorylation; response to oxidative stress; protein kinase cascade; TOR signaling pathway; DNA repair; replicative cell aging | Type 2A-related serine-threonine phosphatase |
SLA1 | Synthetically Lethal with ABP1 | Actin cortical patch assembly; actin filament organization cell wall; organization and biogenesis; endocytosis | Cytoskeletal protein-binding protein; interacts with proteins regulating actin dynamics and endocytosis |
SLA2 | Synthetically Lethal with ABP1 | Actin filament organization; cell polarization cell wall organization and biogenesis; endocytosis; exocytosis | Transmembrane actin-binding protein; links actin to clathrin |
STE3 | STErile | Pheromone-dependent signal transduction during conjugation with cellular fusion; transcribed in alpha cells | Receptor for a factor; mediates pheromone response through MAP kinase cascade |
SUR4 | SUppressor of Rvs | Fatty acid elongation; sphingolipid biosynthesis | Fatty acid elongase activity |
TPD3 | tRNA Processing Deficient | Actin filament organization; cell bud growth; mitotic cell cycle spindle assembly checkpoint protein amino acid dephosphorylation; translation | Regulatory subunit A of protein phosphatase 2A and ceramide-activated protein phosphatase protein serine/threonine phosphatase activity |
VPS20 | Vacuolar Protein Sorting | Late endosome to vacuole transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | Myristoylated subunit of ESCRTIII, the endosomal sorting complex |
VPS21 | Vacuolar Protein Sorting | Transport during endocytosis; protein-vacuolar targeting | GTPase activity |
Obtained from the S. cerevisiae genome database.