Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Illustration of the bundle crossing region of CaV1.2 in the closed channel conformation. Side view of S6 segments with residues Leu-429 and Leu-434 from IS6 and Leu-779 and Ile-781 from IIS6 are shown as spheres. Residues Leu-434 and Leu-779 are part of tight helix-helix packing between segment IS6 and IIS6, whereas residues Ser-435 and Ile-781 interact with neighboring S6 segments. Figure was generated with PyMOL.
