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Mutant VCP translocates to the nucleus from the cytoplasm. VCP translocates to the nucleus and TDP-43 appears more abundant in the cytoplasm of R155C-, R191Q-, and A232E-transfected cells. The graphs show the intensity distribution profile of dsRED-VCP (red line), TDP-43 (green line), and TOPRO-3 (nuclear marker; blue line) in the analyzed cells.
