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DNA strand displacement by TREX2. Stereo figure showing how the TREX2 protein potentially interacts with dsDNA. Lattice packing interactions in the crystal created a pseudo-dsDNA that show the 5′-end abutted against the β1-2 loop. This loop which forms part of the substrate binding pocket may play a role in DNA strand displacement to provide ssDNA to the active site from a DNA duplex.
