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Chimeric SECIS RNAs containing swapped apexes. The apical regions (boxed) of form 2 PHGPx and form 1 SelN SECIS were exchanged (curved arrows) to yield the chimeric PHGPx-ApSelN and SelN-ApPHGPx SECIS harboring the SelN and PHGPx apexes (Ap), respectively. The drawing in the inset schematizes the conserved and variable structural features occurring in forms 1 and 2 SECIS RNAs.
