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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Am J Surg Pathol. 2009 Jan;33(1):22–34. doi: 10.1097/PAS.0b013e31817d7470

Figure 4.

Figure 4

Two subsets of follicular lymphoma arising in the thyroid gland. Visual inspection and unsupervised clustering (Cluster 3.0 and TreeView 1.6) revealed two clinicopathologically distinct groups of cases (cases 1-9 and cases 10-22) which differed significantly with respect to Bcl2 protein expression (p=0.00002), the presence of IGH-BCL2 (p=0.0003), WHO grade (p=0.02), stage at presentation (p=0.0002) and clinical outcome (p=0.007) (Fisher's exact test). CR, complete response; PR, partial response; AND, alive with no disease; AWD, alive with disease (without treatment); DOD, died of disease; IHC, immunohistochemistry; neg, negative; pos, positive.