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Quantitative analysis of three dimensional μCT data for trabecular bone. Analysis of the images collected as described for Figure 4 revealed extensive trabecular bone loss in the ipsilateral (panel A) and contralateral (panel B) distal femur as well as in the L4 vertebra (panel C) compared to control rats. PTX treatment had no effect on trabecular bone loss (panels A through C). (n = 8–16 per cohort). **P < 0.01 and ***P < 0.001 fracture vs. control groups.
