Table 1.
Effects of 4 weeks hypobaric hypoxia (11% O2) on hemodynamic parameters
| Normoxic | Hypoxic | |
|---|---|---|
| BW (g) | 320 ± 18.5 | 273 ± 12.2 |
| HW (mg) | 860 ± 14.8 | 1,125 ± 23.2* |
| RV (mg) | 270 ± 4.5 | 486 ± 14.2* |
| LV + S (mg) | 588 ± 28 | 634 ± 34 |
| RV/LV + S ratio | 0.46 ± 0.01 | 0.96 ± 0.02** |
| RV/BW | 0.84 ± 0.1 | 1.83 ± 0.12** |
| LV + S/BW | 1.86 ± 0.1 | 2.23 ± 0.1 |
Rats were exposed to hypobaric hypoxia (11% O2) for 4 weeks and compared with age-matched normoxic groups. Data are presented as means ± SEM.
P < 0.01 and
P < 0.001 vs. normoxic controls (n = 6 animals per group)