Table 2.
Specificity of C3b Attachment
Compound | Relative Reactivity* |
---|---|
Water | 1 |
Inositol | 56 |
Fucose | 179 |
Glucose | 336 |
Galactose | 360 |
Serine | 366 |
NAc-Glucosamine | 462 |
Mannose | 491 |
Xylose | 674 |
Threonice | 1,575 |
Tyrosine | 17,273 |
The reactive thioester of activated C3 (nascent C3b) covalently reacts with hydoxyl groups in the compounds listed above. Relative reactivcities were calculated from the IC50 concentrations. Note that amino acids exhibited similar reactivities after incorporation into peptides.