Table 3.
Risk factors for development of dialysis-requiring acute renal failure among hospitalized adults
| Unadjusted odds ratio (95% confidence interval) | Multivariablea odds ratio (95% confidence interval) | Multivariablea odds ratio after adjusting for in-patient risk factorsb for ARF (95% confidence interval) | |
|---|---|---|---|
| Baseline GFR (ml per min per 1.73 m2) | |||
| ≥60 | Reference | Reference | Reference |
| 45–59 | 2.38 (2.04–2.79) | 1.95 (1.66–2.30) | 1.66 (1.40–1.97) |
| 30–44 | 10.25 (8.85–11.86) | 6.54 (5.57–7.69) | 4.75 (4.01–5.63) |
| 15–29 | 60.76 (53.38–69.16) | 28.50 (24.50–33.14) | 20.42 (17.40–23.96) |
| <15 | 113.21 (97.31–131.71) | 40.07 (33.75–47.58) | 47.17 (39.22–56.74) |
| Diabetes mellitus | 5.50 (5.00–6.04) | 2.07 (1.86–2.30) | 1.99 (1.78–2.23) |
| Diagnosed hypertension | 4.38 (3.95–4.86) | 1.41 (1.25–1.58) | 1.55 (1.37–1.76) |
| Documented proteinuria | 9.93 (9.04–10.91) | 2.79 (2.49–3.11) | 2.84 (2.52–3.19) |
ARF, acute renal failure; GFR, glomerular filtration rate.
a
Adjusted for all variables shown and also age, sex, and race/ethnicity.
b
Further adjusted for hyperbilirubinemia, intensive care unit stay, sepsis, receipt of mechanical ventilation, coronary artery bypass surgery, other cardiac surgery, percutaneous coronary intervention, and cardiac catheterization including intravenous contrast.