Table 2.
Ideal system performance signal-to-noise ratios on activity concentration estimation, calculated as the ratio of the parameter value to the square-root of the CRB, for presynaptic activity concentration A1, and postsynaptic activity concentration A3.
| A1 | A1 | A3 | A3 | |
|---|---|---|---|---|
| Normal | Simultaneous | Sequential | Simultaneous | Sequential |
| PET | — | 199.2 | ||
| SPECT, ΔE=9.2%, two heads | 107.0 | 77.3 | 33.3 | 24.7 |
| SPECT, ΔE=6.2%, two heads | 113.2 | 79.7 | 38.1 | 26.9 |
| SPECT, ΔE=9.2%, three heads | 130.5 | 94.5 | 40.8 | 30.3 |
| SPECT, ΔE=6.2%, three heads | 138.1 | 97.4 | 46.7 | 33.0 |
| Prodromal PD | ||||
| PET | — | 186.6 | ||
| SPECT, ΔE=9.2%, two heads | 100.1 | 72.3 | 34.0 | 25.2 |
| SPECT, ΔE=6.2%, two heads | 105.9 | 74.6 | 38.8 | 27.4 |
| SPECT, ΔE=9.2%, three heads | 122.2 | 88.4 | 41.6 | 30.8 |
| SPECT, ΔE=6.2%, three heads | 129.3 | 91.2 | 47.5 | 33.6 |
| Early PD | ||||
| PET | — | 175.7 | ||
| SPECT, ΔE=9.2%, two heads | 95.7 | 69.1 | 34.6 | 25.6 |
| SPECT, ΔE=6.2%, two heads | 101.3 | 71.3 | 39.5 | 27.9 |
| SPECT, ΔE=9.2%, three heads | 116.9 | 84.5 | 42.3 | 31.4 |
| SPECT, ΔE=6.2%, three heads | 123.7 | 87.2 | 48.3 | 34.1 |