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Tumor growth curves after s.c. injection of the cells into athymic nude mice. (A) SCL-I cells show steady tumor growth. (B) SCL-I cells with an extra chromosome 15 (SCL-Ichr15 clone 4) were suppressed in their growth during this observation period. (C) An additional copy of chromosome 4 (SCL-Ichr4 clone 1) did not affect tumor growth. Each curve represents an individual animal.
