Table 3.
Pathways analysis network for DTG mice after 6 weeks of induction with Akt1 compared to control mice (P < 0.01)
| Transcript symbol | Transcript name | Fold change |
|---|---|---|
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | +3.9 |
| ALAS2 | Aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | +3.7 |
| CAMK2A | Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha | -2.8 |
| CAMK2D | Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | -2.4 |
| CEACAM1 | Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -2.0 |
| CTGF | Connective tissue growth factor | +2.7 |
| DNAJA | DnaJ (Hsp40) homolog, subfamily A, member 1 | -2.2 |
| ETS1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | -2.3 |
| IFNGR2 | Interferon gamma receptor 2 (interferon gamma transducer 1) | -1.8 |
| HSPCA | Heat shock 90 kDa protein 1, alpha | -2.9 |
| HSPCB | Heat shock 90 kDa protein 1, beta | -2.1 |
| KDR | Kinase insert domain receptor (a type III receptor tyrosine kinase) | +2.7 |
| KRT18 | Keratin 18 | +3.1 |
| MMP3 | Matrix metalloproteinase 3 (stromelysin 1, progelatinase) | +9.2 |
| NRP1 | Neuropilin 1 | +1.9 |
| PTEN | Phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | -1.9 |
| RSN | Restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | -2.0 |
| SERPINA3 | Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | +4.9 |
| SERPINH1 | Serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -3.9 |
| SNCA | Synuclein, alpha (non A4 component of amyloid precursor) | +3.7 |