Table 1.
Cytokine levels in the supernatants from mast cells or T helper type 2 (Th2) cells after various treatments.
| Cytokine levels (pg/ml) |
|||
|---|---|---|---|
| IL-4 | IL-5 | IL-13 | |
| Unactivated mast cell supernatant alone | 4 ± 1 (n = 2) | 35 ± 15 (n = 2) | 18 ± 7 (n = 2) |
| Activated mast cell supernatant alone | 4 ± 2 (n = 2) | 44 ± 21 (n = 2) | 69 ± 24 (n = 2) |
| Th2 cells (∼5 × 106) + medium | 4 ± 2 (n = 8) | 228 ± 40 (n = 8) | 608 ± 95 (n = 8) |
| Th2 cells (∼5 × 106) + unactivated mast cell supernatant | 5 ± 1 (n = 4) | 257 ± 45 (n = 5) | 636 ± 90 (n = 8) |
| Th2 cells (∼5 × 106) + activated mast cell supernatant | 20 ± 7 (n = 4) | 780 ± 81 (n = 5) | 2215 ± 423 (n = 8) |
| Th2 cells (∼5 × 106) + 100 nM PGD2 | 24 ± 9 (n = 8) | 695 ± 40 (n = 8) | 2360 ± 379 (n = 8) |
IL, interleukin; PGD2, prostaglandin D2.