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Poly IC induces the production of p402 and p40 but not IL-12 in mouse peritoneal macrophages (A) and primary microglia (B). Cells were treated with IL-1β (20 ng/mL), IFN-γ (12.5 U/mL), and poly IC (50 μg/mL) under serum-free condition. At different times of stimulation, supernatants were used for quantification of p402, p40, and IL-12 by sandwich ELISA. Data are mean ± SD of three different experiments.
