Fig. 9.

Up- and downregulation of genes in HA-treated cells for 14 days. Each function has several genes that have been produced by replicate analysis with duplication (p < 0.05). UBD indicates ubiquitin D (FAT10); HGS, hepatocyte growth factor-regulated tyrosine kinase substrate; SLC31A1, solute carrier family 31 (copper transporters); KIFAP3, kinesin-associated protein 3; AXIN2, axin 2 (conductin, axil); FKBP1A, FK506-binding protein 1A (12 kDa); VDAC3, voltage-dependent anion channel 3; ADAM22, ADAM metallopeptidase domain 22; MEKK1, mitogen-activated protein kinase kinase kinase 1; SLC25A32, solute carrier family 25, member 32; RIPK2, receptor-interacting serine–threonine kinase 2; ILF3, interleukin enhancer binding factor 3 (90 kDa); BAX, BCL2-associated X protein; BCL2L14, BCL2-like 14 (apoptosis facilitator), FMNL2, formin-like 2; ARL3, ADP-ribosylation factor-like 3; ING3, inhibitor of growth family, member 3, SRP19, signal recognition particle 19 kDa, RAB24, member RAS oncogene family; VPS16, vacuolar protein sorting 16 homolog; KALRN, kalirin, RhoGEF kinase; MUC3, mucin-3; DEFA3, defensin, alpha 3; ATF3, activating transcription factor 3; PCDHB15, protocadherin beta 15; HRH3, histamine receptor H3