Fig. 3.

Single-cell culture analysis of O4+ oligodendrocyte survival after 44 hours in the presence of rEPF; comparison with other growth factors. (a) IGF-1, (b) PDGF, (c) bFGF, (d) insulin, (e) pGEX-rEPF/cpn 10 and BV-rEPF/ cpn 10 all promoted O4⁺oligodendrocyte survival over prolonged periods (44 hours) of single-cell culture. Data represent the mean percentage of viable cells after 44 hours of culture +SEM of four to five separate experiments. The significance of difference between means was measured using ANOVA with Tukey’s posttest