Skip to main content
. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Virus Res. 2008 Aug 15;139(2):148–156. doi: 10.1016/j.virusres.2008.07.007

Fig. 5. Comparison of a tRNA-mRNA interaction and the domain 3/P-site domain structure from the CrPV IRES RNA.

Fig. 5

At left is the structure of an initiator methionine tRNA interacting with an AUG start codon in the P-site of the ribosome, extracted from a structure of a bacterial ribosome bound to all three tRNAs and mRNA (Selmer et al., 2006). At right is the crystal structure of the P-site domain (domain 3) of the CrPV IRES. In both structures, some nucleotides have been removed for clarity. The location of the anticodon and codon elements are shown, analogous bases are colored to match each other, and the locations of nucleotides mentioned in the main text are shown.