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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Immunol Rev. 2009 Mar;228(1):93–114. doi: 10.1111/j.1600-065X.2008.00757.x

Fig. 5. Itk-deficient mice develop a large population of innate-type CD8+ T cells in the thymus.

Fig. 5

A comparison with Vav1-deficient mice is shown. Left: CD4 versus CD8 flow plots of thymi. Right: expression of CD44 on gated CD8 SP cells demonstrating that Itk−/− CD8 SP cells express high levels of the memory marker CD44, whereas Vav−/− CD8 SP cells do not.