Table 3.

Phenotypic comparison of male and female wild type and Agpat2^−/− mice fed chow or a fat-free diet for two weeks

	Wild type				Agpat2−/−
Gender	Male		Female		Male		Female
Diet	Chow (6% fat)	Fat-free (0.2% fat)	Chow (6% fat)	Fat-free (0.2% fat)	Chow (6% fat)	Fat-free (0.2% fat)	Chow (6% fat)	Fat-free (0.2% fat)
Number	6	5	4	4	5	6	4	5
Age, weeks	11–14	9.5–11.5	27–28	26–29	12–15	9.5–11.5	27–29	27–29
Body weight, g	28.3 ± 3.0	25.5 ± 3.9	21.9 ± 0.75	23.8 ± 1.6	28.7 ± 4.5	22.2 ± 5.0	22.3 ± 2.6	17.6 ± 0.36
Liver weight, g	1.50 ± 0.18	1.51 ± 0.20	0.98 ± 0.08	1.37 ± 0.29	4.56 ± 1.23	3.30 ± 1.16	3.60 ± 0.73	2.73 ± 0.25
Liver TG, mg/g	5.72 ± 1.6	16.8 ± 5.26	14.9 ± 4.1	29.0 ± 10	51.7 ± 18.4	22.6 ± 7.4†	49.3 ± 9.1	24.7 ± 9.3*
Plasma TG, mg/dL	100 ± 39	118 ± 31	68.0 ± 3.7	77.0 ± 28	194 ± 26	45.1 ± 105†	156 ± 101	41.2 ± 31.7#
Insulin, ng/mL	2.06 ± 1.06	2.70 ± 1.34	1.30 ± 0.062	1.82 ± 0.62	59.0 ± 36	79.6 ± 80	58.1 ± 11	40.3 ± 16
Glucose, mg/dL	255 ± 20	281 ± 19	297 ± 18	322 ± 41	591 ± 87	443 ± 156	425 ± 84	391 ± 141
Free fatty acids, meq/L	0.57 ± 0.19	0.63 ± 0.12	0.37 ± 0.06	0.34 ± 0.08	0.43 ± 0.09	0.21 ± 0.04†	0.37 ± 0.08	0.23 ± 0.05*

Wild type and Agpat2^−/− mice of both sexes were fed ad libitum a rodent chow that contained 6.0% fat or a fat-free diet (0.2% fat) for 2 weeks. Each value represents the mean ± S.D.

^#p=0.05,

^*p<0.05;

^†p<0.01; between the chow diet and the fat free diet for the same genotype and gender.