Table 4.

Proportional Hazards Model: Continuous Hormone Therapy Duration

Comparison	Unadjusted			Adjusted*
	HR	95% CI	P†	HR	95% CI	P†
Overall survival‡	0.88	0.83 to 0.93	< .0001	0.86	0.81 to 0.91	< .0001
Disease-free survival‡	0.86	0.82 to 0.90	< .0001	0.85	0.80 to 0.89	< .0001
Cause-specific mortality§	0.81	0.70 to 0.94	.004	—‖		—
Local failure§	0.92	0.85 to 1.00	.052	—		—
Distant metastasis§	0.78	0.69 to 0.89	.0002	—		—

Abbreviation: HR, hazard ratio.

^*HR is adjusted for age (< 70 [reference level] or ≥ 70 years), radical prostatectomy (yes [reference level] or no), nodal status (negative [reference level] or positive), centrally reviewed Gleason score (2 to 6 [reference level] v 7 v 8 to 10), and stage (A/B [reference level] or C).

^†P value from χ² test.

^‡Cox proportional hazards model was used.

^§Fine and Gray's model was used.

^‖The number events are too few to have stable estimates.