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Kaplan-Meier plots of overall survival (OS) and progression-free survival (PFS) in the (A) heavily pretreated and (B) minimally pretreated cohorts. The median OS and PFS rates were 10.8 months (95% CI, 8.6 to 14.5 months) and 3.8 months (95% CI, 2.7 to 5.4 months), respectively, in the heavily pretreated and 13.1 months (95% CI, 10.9 to 17.6 months) and 4.2 months (95% CI, 3.6 to 6.0 months), respectively, in the minimally pretreated cohorts.
