Table 4.
Comparison of the combined prevalence of tested genetic polymorphisms
| Genetic polymorphism | Observation group | Control group | Odds ratio | 95% confidence interval | p Value (Fisher’s exact test) |
|---|---|---|---|---|---|
| MTHFR* (%) | 56 | 31 | 2.89 | 1.40–5.96 | 0.006† |
| MTHFR* and factor V Leiden (%) | 6 | 1 | 5.36 | 0.54–53.01 | 0.143 |
| MTHFR* and PAI-1 4G/4G (%) | 42 | 25 | 2.21 | 1.05–4.66 | 0.053 |
| Factor V Leiden and PAI-1 4G/4G (%) | 8 | 2 | 3.61 | 0.64–20.46 | 0.194 |
| Prothrombin G20210A and PAI-1 4G/4G (%) | 4 | 2 | 1.73 | 0.24–12.67 | 0.627 |
* Both heterozygous or at least one homozygous; †significant; MTHFR = methylenetetrahydrofolate reductase; PAI-1 = plasminogen activator inhibitor 1.