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Means of ABR threshold shifts at 10 (A), 20 (B), and 40 kHz (C) following local saline or 3-NP application on postoperative days (POD) 1, 7, and 14. Local applications of 3-NP have significant interactions with threshold shifts at all the frequencies (p < 0.0001, two-way factorial ANOVA). Asterisks indicate significant differences to the control group in threshold shifts by multiple comparisons with the Tukey–Kramer test. Bars represent standard errors.
