Table 5. Confirmatory p-value combination analysis.
CHR | SNP pair/triplet/quartet | Combined samples | Independent samples | ||
ULR-NOMINAL | ULR-ORDINAL | ULR-NOMINAL | ULR-ORDINAL | ||
−log10(p) | −log10(p) | −log10(p) | −log10(p) | ||
2 | rs9308945 - rs6711736 | 5.4738 | 6.5331 | 1.3426 | 2.8468 |
2 | rs6711736 - rs6729869 | 5.1218 | 5.8471 | 2.4989 | 1.5654 |
2 | rs6729869 - rs10495809 | 3.5135 | 4.1433 | 1.1672 | 1.0110 |
2 | rs9308945 - rs6711736 - rs6729869 | 7.1739 | 8.3979 | 2.1520 | 2.4655 |
2 | rs6711736 - rs6729869 - rs10495809 | 5.8055 | 6.9586 | 2.1520 | 1.3721 |
2 | rs9308945 - rs6711736 - rs6729869- rs10495809 | 7.8469 | 9.5155 | 1.9102 | 2.2028 |
SNP pairs, triplets and quartets that were identified by the p-value combination method in GWAS were verified in CMAS. Truncated product p-value statistics were calculated by combing single p values from the previous single-locus ULR-NOMINAL analysis or ULR-ORDINAL analysis in CMAS. The exact p values (in −log10 scale) for the combined and independent samples are shown.