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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Hepatology. 2009 Apr;49(4):1375–1384. doi: 10.1002/hep.22927

Figure 3.

Figure 3

Immunohistochemical staining for lumican. Moderate stromal staining was seen in portal areas. Staining intensity for lumican in hepatocytes varied between study groups, with more intense staining occurring in NASH-mild (3c) and NASH-severe (3d) than in simple steatosis (3b) or obese normal (3a) biopsies. Hepatocyte staining was cytoplasmic and was apparent throughout the parenchyma but most notable in zones 2–3 in a mosaic pattern. Mild sinusoidal staining was seen. The pattern of lumican staining closely paralleled the fibrosis.