Table 2.
Transcript-specific RNA interference
|
DTC migration defects |
||||||
|---|---|---|---|---|---|---|
| RNAi method | Target | Genotype | Development | Class-l | Class-s | n |
| Injection | mig-6S and L | Wild type | Embryonic/L1 arrest | - | - | |
| mig-6S | Wild type | Embryonic/L1 arrest | - | - | ||
| mig-6L | Wild type | Normal | 100% | - | >100 | |
| Feeding | mig-6S and L | Wild type | Normal | 100% | - | >100 |
| mig-6S | Wild type | Normal | 0% | 0%(A), 6%(P)* | 152 | |
| mig-6L | Wild type | Normal | 100% | - | >100 | |
| Feeding | mig-6S | rrf-3 | Normal | 0% | 6%(A), 37%(P)† | 63 |
*
Phase 2V and D defects are predominant.
†
Phase 2M defect is predominant.