Table 1.

Baseline demographic, genetic, biochemical and clinical characteristics in mild-to-moderate AD (n = 32)^*

Age, y	71 (7)
Female, (%)	10 (31)
Education years	14 (3)
APOE ε4 carriers, (%)	24 (74)
BP systolic, mm Hg	144 (23)
BP diastolic, mm Hg	77 (11)
Body Mass Index	27 (5)
Hachinski Ischemia Score	0.6 (1.0)
Ascorbic acid supplementation present, (%)	34.4
Ascorbic acid, CSF (µM)	129 (52)
Ascorbic acid, plasma (µM)	41 (30)
CSF-to-plasma ascorbic acid ratio	4.0 (1.6)
Albumin, CSF (µM)	30.5 (16)
Albumin, serum (µM)	4052.5 (371.3)
CSF Albumin Index	7.5 (3.8)
Mini Mental Status Exam	19 (5)
Alzheimer’s Disease Assessment Scale – cognitive subscale	24 (10)
Clinical Dementia Rating – sum of box score	5.9 (1.4)
Annual change in Mini Mental State Exam	3.3 (3.8)
Annual change in Alzheimer’s Disease Assessment Scale –cognitive subscale	8.9 (9.1)
Annual change in Clinical Dementia rating – sum of box score	6.8 (2.7)

^*Mean (SD) unless denoted otherwise.