Table 1.

MALDI-MS identification of proteins demonstrating significant changes in expression in BoNT/A injected rat TA muscle compared with uninjected control.

Spot ID	Protein identified	Theoretical MW (kDa)/pI	Experimental MW (kDa)/pI	Sequence coverage (%)	Swiss-Prot/NCBI accession number
1	Superoxide dismutase [Mn]	22.3/7.94	23.9/8.43	74.2	P07895
2	ATP synthase D chain	18.6/6.21	22.6/6.11	61.9	P31399
3	Unidentified		18.6/5.53
4	ATP synthase α-chain	55.3/8.28	53.3/7.79	49.4	P15999
5	a) Hsp60	57.9/5.35	65.9/5.60	62.0	P63039
	b) α-actin	41.8/5.23		26.7	P68035
6	β-enolase	46.9/6.81	48.6/7.03	51.2	P21550
7	Tropomyosin β-chain	32.8/4.66	35.2/5.07	56.3	P58775
8	MyHC IIb	61.0/5.40	28.8/6.53	28.8	GI:9581821
9	Protein disulfide isomerase	55.0/4.77	63.4/5.25	52.2	P04785
10	β-enolase	46.9/6.81	46.2/7.74	53.8	P21550
11	a) Troponin T, fast skeletal muscle	30.6/6.18	33.7/6.54	48.1	P09739
	b) Creatine kinase M-type	43.0/6.58		24.4	P07310
12	Prohibitin	29.8/5.57	28.9/5.65	62.5	P67779
13	a) MyHC IIb	61.0/5.40	60.0/5.67	58.3	GI:9581821
	b) VDBP	51.8/5.41		37.2	P04276
	c) α-actin	41.8/5.23		37.1	P68035
14	Tufm protein	47.2/7.60	47.4/6.55	42.5	GI:38173913
15	Unidentified		33.4/5.59
16	Peroxiredoxin-3	21.6/5.81	26.5/6.16	70.8	Q9Z0V6
17	ATP synthase β-subuit	51.7/4.95	54.5/5.31	76.6	P10719
18	Troponin T, fast skeletal muscle	30.6/6.18	36.7/5.67	38.4	P09739
19	Unidentified		31.5/7.62
20	PEBP 1	20.7/5.48	24.5/5.54	72.6	P31044
21	Unidentified		46.4/5.44
22	Unidentified		31.8/6.53
23	GAPDH	35.7/8.18	33.8/6.20	50.3	P04797
24	a) GAPDH	35.7/8.18	29.3/7.75	26.2	P04797
	b) Posssible: Aldolase A	39.2/8.40		22.3	P05065
25	MyHC IIb	61.0/5.40	32.7/7.10	34.8	GI:9581821