Table 2.
Candidate Genes in Relation to Coronary Atherosclerosis and Myocardial Infarction
| Gene | OMIM gene ID | Chromosome | Substitution (SNP rs#) | subPSEC | Pdeleterious | Reference |
|---|---|---|---|---|---|---|
| ALOX5AP | 603700 | 13q12 | Y133H (rs41323349) | -0.31 | 0.06 | [220] |
| LTA4H | 151570 | 12q22 | T600S (rs1803916) | -2.62 | 0.41 | [220] |
| BMPR1A | 601299 | 10q22.3 | R443C (rs35619497) | -8.29 | 0.99 | [211] |
| LGALS2 | 150571 | 22q13.1 | A25P (rs9607476) | -1.86 | 0.24 | [230] |
| V119I (rs2235339) | -0.99 | 0.12 |
ALOX5AP arachidonate 5-lipoxygenase-activating protein, LTA4H leukotriene A4 hydrolase, BMPR1A bone morphogenetic protein receptor type, LGALS2 lectin galactoside-binding soluble 2, OMIM online mendelian inheritance in man, q long arm of a chromosome, SNP single nucleotide polymorphism, * http://www.ncbi.nlm.nih.gov/ (Genome build 36.1).