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. Author manuscript; available in PMC: 2009 Apr 28.
Published in final edited form as: J Cardiovasc Pharmacol. 2008 Jul;52(1):82–89. doi: 10.1097/FJC.0b013e31817f9379

Figure 2.

Figure 2

Effect of intravenous CARTp administration on pial arteriolar diameter. Intravenous injection of 1.5-mL saline vehicle produced a slight constriction in pial arterioles. CARTp administration (30 μg/kg) caused a significantly greater constriction effect (P <0.05, 1-way ANOVA CARTp vs saline). Blockade of β-adrenergic receptors with 2 mg/kg IV propranolol prior to systemic CARTp administration did not alter the magnitude or time course of CARTp-evoked cerebrovasoconstriction.