. Author manuscript; available in PMC: 2010 Apr 1.

Published in final edited form as: Genet Epidemiol. 2009 Apr;33(3):183–197. doi: 10.1002/gepi.20364

TABLE IV.

Regression of simulated power on six properties for each association statistic (in the presence of genotyping errors); p value < 0.01

Properties	Geno-sim	Haplo-sim	Geno-LRT	Can-cor	Haplo-score	Haplo-match	Haplo-max
Marker informativity	1.57 (0.0075)	1.62 (0.0069)	1.32 (0.0007)	1.31 (0.0008)	1.01 (0.0035)
3 Markers			0.34 (<.0001)	0.30 (<.0001)	0.24 (<.0001)		0.22 (<.0001)
7 Markers			0.28 (<0001)	0.25 (<.0001)	0.18 (<.0001)	0.17 (0.0022)	0.23 (<.0001)
Causal allele frequency	1.07 (<.0001)	0.99 (0.0002)	1.13 (<.0001)	1.25 (<.0001)	1.13 (<.0001)	1.50 (<.0001)	1.30 (<.0001)
Preponderance Index							0.22 (0.0176)^a
LD pattern	0.42 (<.0001)	0.44 (<.0001)	0.20 (0.0001)	0.21 (<.0001)	0.16 (0.0007)	0.23 (0.0004)	0.21 (0.0003)

Although this p value was greater than 0.01, we kept it for comparison with Table III.

The simulated power of each method was regressed on the six properties (“3 markers” and “7 markers” are indicator variables, while others are continuous variables). The parameter estimates of significant variables are listed, with p values given in parentheses. LD, linkage disequilibrium.