Table. List of the allelic frequencies of LOXL1 variants reported in different populations.
Summary of representative studies reporting on the allelic frequencies of SNPs rs3825942 and rs1048661 in the LOXL1 gene related to pseudoexfoliation syndrome and glaucoma.
| Population | Affection status | rs3825942 (%) | rs1048661 (%) | Reference | ||
|---|---|---|---|---|---|---|
| Iceland | Control | 85 | 65 | 26 | ||
| XFG | 99 | 83 | 26 | |||
| XFS | 98 | 79 | 26 | |||
| Sweden | Control | 88 | 68 | 26 | ||
| XFG | 100 | 83 | 26 | |||
| XFS | n/a | n/a | 26 | |||
| United States | Control | 84 | 67 | 30 | ||
| XFG | 94 | 79 | 30 | |||
| XFS | n/a | n/a | 30 | |||
| United States | Control | 99 | 60 | 31 | ||
| XFG | n/a | n/a | 31 | |||
| XFS | 88 | 82 | 31 | |||
| India | Control | 74 | 63 | 33 | ||
| XFS/XFG | ||||||
| combined | 92 | 72 | 33 | |||
| Japan* | Control | 86 | 54 | 35 | ||
| XFG | 100 | 100 | 35 | |||
| XFS | 100 | 100 | 35 | |||
The asterick (*) denotes that the reported frequencies in the Japanese are for the “T” allele of rs1048661. All other allelic frequencies are for the respective “G” allele.