Table 3.
[64Cu]Cu-PTSM Displacement from HSA Binding by Fatty Acids
| % Free [64Cu]Cu-PTSM ± SD (n)1 | |||||
|---|---|---|---|---|---|
| Fatty | Acid | Capric | Myristic | Palmitic | Oleic |
| Ratio | 1:1 | 7.5 ± 0.3 (4) | 6.8 ± 0.3 (4) | 5.6 ± 0.2 (3) | 6.0 ± 0.3 (4) |
| 6:1 | 12.6 ± 3.5 (5) | 14.6 ± 0.8 (5) | 9.6 ± 0.3 (4) | 12.7 ± 0.7 (4) | |
The value of unbound [64Cu]Cu-PTSM in fatty acid-free (HSA + ethanol) solutions was 4.5 ± 0.2%.