Table A2.
summary of Canonical Pathway and Involved Genes
| Canonical pathway | Involved genes | p |
| Apoptosis signaling | MAPK3 | 0.001 |
| B cell receptor signaling | MAPK3 | 0.001 |
| Calcium signaling | MAPK3 | 0.001 |
| cAMP-mediated signaling | MAPK3 | 0.001 |
| Chemokine signaling | MAPK3 | 0.001 |
| EGF signaling | MAPK3 | 0.001 |
| ERK/MAPK signaling | ESR1 | 0.046 |
| MAPK3 | 0.001 | |
| Estrogen receptor signaling | ESR1 | 0.046 |
| MAPK3 | 0.001 | |
| Fc epsilon RI signaling | MAPK3 | 0.001 |
| FGF signaling | MAPK3 | 0.001 |
| G-protein-coupled receptor signaling | MAPK3 | 0.001 |
| Glyoxylate and dicarboxylate metabolism | HAO2 | 0.003 |
| GM-CSF signaling | MAPK3 | 0.001 |
| IGF-1 signaling | MAPK3 | 0.001 |
| IL-10 signaling | MAPK3 | 0.001 |
| IL-2 signaling | MAPK3 | 0.001 |
| Integrin signaling | MAPK3 | 0.001 |
| JAK/Stat signaling | MAPK3 | 0.001 |
| PDGF signaling | MAPK3 | 0.001 |
| PI3K/AKT signaling | MAPK3 | 0.001 |
| PPAR signaling | MAPK3 | 0.001 |
| PTEN signaling | MAPK3 | 0.001 |
| T cell receptor signaling | MAPK3 | 0.001 |
| TGP-β signaling | MAPK3 | 0.001 |
| VEGF signaling | MAPK3 | 0.001 |
p value from Fisher's exact test determines the probability that the association between the gene involved and the canonical pathway is explained by chance alone.