Table 4.

Histomorphometry: Cortical Bone

	WT	PAPP-A KO	p
2 mo
MS/BS	40.3 ± 3.37	35.5 ± 4.18	0.388
MAR	1.39 ± 0.164	0.96 ± 0.112	0.074
BFR/NS	236 ± 36	159 ± 19	0.125
6 mo
MS/BS	18.4 ± 1.61	21.7 ± 2.79	0.324
MAR	0.670 ± 0.051	0.750 ± 0.014	0.188
BFR/BS	86 ± 8	91 ± 6	0.448

Values are mean ± SE, n = 6–9 per group.

MS/BS, mineralizing surface/bone surface (%); MAR, mineral apposition rate (μm/d); BFR/BS, bone formation rate/bone surface (μm³/μm²/yr).