Table 7.

Expression of IGF System Components in WT and PAPP-A KO Bone

	Copies mRNA/μg total RNA
	WT	PAPP-A KO	p
IGF-I	575 ± 118	598 ± 69	0.86
IGF-IR	352 ± 108	370 ± 85	0.90
IGFBP-4	1450 ± 546	1830 ± 1290	0.81
IGFBP-5	10,100 ± 1,380	8,250 ± 1,360	0.36

RNA was harvested from tibia of WT (n = 7) and PAPP-A KO (n = 9) mice.

Results (mean ± SE) are expressed as copies of mRNA per microgram total RNA.