Table 1.
Effects of ASI on FS (%)
| After treatment | |||||
| Group | Dose (mg/kg/day) | Normal | Before treatment | 1 week | 2 weeks |
| Sham | - | 73.0 ± 5.7 | 68.8 ± 6.5 | 70.9 ± 3.4 | 66.1 ± 8.0 |
| Model | - | 68.8 ± 10.1 (0.2193) | 30.8 ± 5.0+++ | 26.1 ± 6.6+++ | 22.7 ± 7.6+++ |
| ASI | 0.1 | 72.8 ± 3.6 (0.2417) | 28.9 ± 4.6 (0.4213) | 34.2 ± 7.5* (0.0163) | 27.4 ± 7.8 (0.2620) |
| ASI | 0.3 | 72.1 ± 9.6 (0.3329) | 28.8 ± 6.9 (0.3973) | 41.5 ± 11.3*** | 28.8 ± 8.9 (0.1474) |
| ASI | 1.0 | 68.4 ± 6.7 (0.9061) | 31.7 ± 2.5 (0.7024) | 42.9 ± 7.7*** | 35.8 ± 13.2** (0.0028) |
| Quinapril | 1.0 | 70.1 ± 7.5 (0.7016) | 30.2 ± 4.7 (0.7989) | 42.4 ± 4.7*** | 31.4 ± 8.8* (0.0411) |
Note: Values are mean ± SD in each group (n = 10). +++P < 0.001: statistical significance over the sham group (comparison of group means after ANOVA). *P < 0.05, **P < 0.01, ***P < 0.001: statistical significances over the model group (comparison of group means after ANOVA). No statistical significance between ASI (1.0 mg/kg/day) and Quinapril treatments. Exact P values are available in brackets.