Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Enzymes of bile acid synthesis. The 16 enzymes and the 17 reactions they catalyze in converting cholesterol into a conjugated bile salt are shown. Mutations causing human disease have been identified in the nine enzymes that are boxed in blue (adapted from Ref. 33). The structures of cholesterol and a generic conjugated bile salt are shown. R = OH or H; X = glycine or taurine.
