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. 2009 Apr;50(Suppl):S440–S445. doi: 10.1194/jlr.R800028-JLR200

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Copyright © 2009, American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 1. — Structures and metabolic pathway of gangliosides (9). The nomenclature for gangliosides and related GSLs is based on that of Svennerholm (49). ARSA, arylsulfatase A; β-gal, lysosomal acid β-galatosidase; CST, cerebroside sulfotransferase; GALC, galactosylceramidase; GalCer, galactosylceramide; GalNAcT, GA2/GM2/GD2/GT2 synthase; GalT-I, LacCer synthase; GalT-II, GA1/GM1/GD1b/GT1c synthase; GalT-III, GalCer synthase; GlcT, GlcCer synthase; GM2A, GM2 activator protein; HEX, β-N-acetylhexosaminidase; SAP, saposin; ST-I, GM3 synthase; ST-II, GD3 synthase; ST-III, GT3 synthase; ST-IV, GM1b/GD1a/GT1b/GQ1c synthase; ST-V, GD1c/GT1a/GQ1b/GT3 synthase; ST-VII, GD1a/GT1aα/GQ1bα/GP1cα synthase.