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. Author manuscript; available in PMC: 2009 Apr 29.
Published in final edited form as: J Med Primatol. 2008 Feb;37(1):26–30. doi: 10.1111/j.1600-0684.2007.00221.x

Fig. 2.

Fig. 2

Effect of Pegasys treatment in chronic SIV-infected macaques. Panel A: Plasma viral RNA levels for Pegasys-treated (Brown symbols) and untreated (Blue symbols) monkeys are reported as log10 viral RNA copies per ml of plasma. Panel B: T-cell proliferative responses are shown for various time points after Pegasys treatment initiation. The y-axis shows the Stimulation Index (SI) as calculated by cpm of SIV-stimulated PBMC/cpm of media control cultures. Panels C and D show the increase in 2′–5′ oligoadenylate synthetase (OAS) and Mx PBMC mRNA levels, respectively, compared with OAS and Mx PBMC mRNA levels in the same animal prior to treatment.