Figure 1. Non-conserved expression and targeting of miR-7.
(A–C) Localization of miR-7 RNA (purple) and Sens protein (green) in developing antenna (A), leg (B) and wing (C) discs. The miR-7 RNA is detected in the cytoplasm of proprioceptor and olfactory SOP cells, which are marked with Sens-positive nuclei. Comparable sensory organs in vertebrates do not express miR-7.
(D) Overlap of predicted miR-7 targets in Drosophila and human is limited to nine orthologous genes.