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The IC50 (μM) of curcumin and its analogues, GO-Y030, FLLL-11, and FLLL-12 in human colon cancer cells and WI-38 human lung fibroblasts
| HCT116 (IC50 μM) |
HT-29 (IC50 μM) |
SW480 (IC50 μM) |
WI-38 (IC50 μM) |
|
|---|---|---|---|---|
| Curcumin | 10.91 | 13.31 | 10.26 | 48.82 |
| GO-Y030 | 0.61 | 0.96 | 0.51 | 13.78 |
| FLLL-11 | 2.07 | 4.48 | 1.64 | >1000.00 |
| FLLL-12 | 2.49 | 3.35 | 1.17 | >1000.00 |
*Cancer cells were treated for 72 hours and cell viability was determined by MTT assays and IC50 values were analyzed.
