. 2009 Apr;7(2):111–117. doi: 10.1089/met.2008.0030

Table 5.

Odds Ratios for Metabolic Syndrome in 532 Apparently Healthy Caucasian Women in the Women's Health Study, According to ESR1 and ESR2 Haplotype, and Assuming an Additive Model

	Odds ratio, unadjusted (95% CI)	P
ESR1 (rs2234693, rs9340799)
T-A	Referent (1.0)
C-A	1.27 (0.82–1.96)	0.28
C-G	1.08 (0.79–1.48)	0.64
ESR2 (rs1271572, rs1256049, and rs4986938)
T-G-G^a	Referent (1.0)
G-G-G	0.85 (0.55–1.31)	0.46
G-G-A	1.13 (0.79–1.60)	0.51

Remaining possible haplotypes with ≤10% frequency were not considered.

^{^a}

G denotes major allele at each site: rs1271572, rs1256049, and rs4986938; A denotes minor allele at sites rs1256049 and rs4986938; and T denotes minor allele at rs1271572.

Abbreviations: OR, odds ratio; CI, confidence interval.